Impronacine 5mg,10mg

 

 

 

Impronacine 5mg,10mg

Composition:

Each film coated tablet contains:

Active ingredients:

Solifenacin succinate ……………………………. 5, 10 mg

Inactive ingredients:

Core:

Lactose monohydrate, Pregelatinized starch, Magnesium stearate, Colloidal silicon dioxide ( Aerosil 200 ) & Maize starch.

Indications:

Impronacin film coated tablets is a muscarinic antagonist indicated for the treatment of overactive bladder

with symptoms of urge urinary incontinence, urgency, and urinary frequency

Dosage & administration:

  • Dosing Information

The recommended dose of Impronacin film coated tablets is 5 mg once daily. If the 5 mg dose is well

tolerated, the dose may be increased to 10 mg once daily. Impronacin film coated tablets should be taken

with water and swallowed whole. Impronacin film coated tablets can be administered with or without food.

  • Dose Adjustment in Patients with Renal Impairment

For patients with severe renal impairment (CLcr <30 mL/min), a daily dose of Impronacin film coated tablets

greater than 5 mg is not recommended.

  • Dose Adjustment in Patients with Hepatic Impairment

For patients with moderate hepatic impairment (Child-Pugh B), a daily dose of Impronacin film coated tablets

greater than 5 mg is not recommended. Use of Impronacin film coated tablets in patients with severe hepatic

impairment (Child-Pugh C) is not recommended

  • Dose Adjustment in Patients Taking CYP3A4 Inhibitors

When administered with potent CYP3A4 inhibitors such as ketoconazole, a daily dose of

Impronacin film coated tablets greater than 5 mg is not recommended.

Package & storage:

– Carton box containing a blister (PVC/Alu) of 10 tablets and insert leaflet.

– Store in cool & dry place at a temperature not exceeding 30 °C.

– Keep out of the reach of children.

– Do not use unless under physician supervision.

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