Itopride

Composition:
Each tablet contains:
– Active ingredients:

Itopride hydrochloride…… . .. . … … … …50 mg

Pharmacological action:

– Itopride hydrochloride activates gastrointestinal propulsive motility due to its dopamine D2 antagonizingactivity and acetyl cholinesterase inhibitory activity. It activates acetylcholine release and inhibits itsdegradation.
– Itopride hydrochloride also has antiemetic action through interaction with D2 receptors located in thechemoreceptor trigger zone.
-Itopride hydrochloride has been shown to accelerate gastric emptying in humans.
-The action of ltopride hydrochloride is highly specific forthe upper gastrointestinal tract. Itopride hydrochloridedoes not affect serum gastrin levels.

Indications:

Itopride hydrochloride is used in the treatment of gastrointestinal symptoms of:
– Functional dyspepsia.
– Non-ulcer dyspepsia (chronic gastritis) i.e.: sensation of bloating, early satiety, upper abdominal pain ordiscomfort, anorexia, heartburn, nausea & vomiting.

Dosage & administration:

-The recommended dose of Itopride hydrochloride for adult patients is 150 mg daily [one tablet (50 mg) takenorally three times a day before meals).
– The dose may be reduced according to the patient’s age & symptoms.

Package & Storage:

– Carton box containing a blister (PVc/Alu) of 10 tablets.
– Store in a dry place at a temperature not exceeding to 250 C away from sunlight.
– To be used under physician supervision

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